Randomized, open-label, comparative phase IV study on the bioavailability of Ciclosporin Pro (Teva) versus Sandimmun® Optoral (Novartis) under fasting versus fed conditions in patients with stable renal transplants

BACKGROUND: The influence of pre- or postprandial administration on pharmacokinetics of cyclosporine is supposed to be less in gel-based formulations than in microemulsions. This study was designed to investigate the influence of a high-fat meal on the pharmacokinetic profile of the two cyclosporine...

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Detalles Bibliográficos
Autores principales: Gäckler, Anja, Dolff, Sebastian, Rohn, Hana, Korth, Johannes, Wilde, Benjamin, Eisenberger, Ute, Mitchell, Anna, Kribben, Andreas, Witzke, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518767/
https://www.ncbi.nlm.nih.gov/pubmed/31088392
http://dx.doi.org/10.1186/s12882-019-1340-z

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