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Ruxolitinib in combination with prednisone and nilotinib exhibit synergistic effects in human cells lines and primary cells from myeloproliferative neoplasms
Ruxolitinib is the front-line non-palliative treatment for myelofibrosis (MF). However, a significant number of patients lose or present suboptimal response, are resistant or have unacceptable toxicity. In an attempt to improve response and avoid the adverse effects of this drug, we evaluated the co...
Autores principales: | Cortés, Alicia Arenas, Diaz, Rosa Ayala, Hernández-Campo, Pilar, Gorrochategui, Julián, Primo, Daniel, Robles, Alicia, Morales, María Luz, Ballesteros, Joan, Rapado, Inmaculada, Gallardo, Miguel, Linares, María, Martínez-López, Joaquín |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518898/ https://www.ncbi.nlm.nih.gov/pubmed/30545926 http://dx.doi.org/10.3324/haematol.2018.201038 |
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