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Finely-tuned regulation of AMP-activated protein kinase is crucial for human adult erythropoiesis

AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells. Indeed, Ampk α1(−/−), Ampk β1(−/−) and Ampk γ1(−/−) mice develop hemolytic anemia and the plasma membrane of their red blood cells...

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Detalles Bibliográficos
Autores principales: Ladli, Meriem, Richard, Cyrielle, Aguilar, Lilia Cantero, Ducamp, Sarah, Bondu, Sabrina, Sujobert, Pierre, Tamburini, Jérôme, Lacombe, Catherine, Azar, Nabih, Foretz, Marc, Zermati, Yael, Mayeux, Patrick, Viollet, Benoit, Verdier, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518903/
https://www.ncbi.nlm.nih.gov/pubmed/30309849
http://dx.doi.org/10.3324/haematol.2018.191403