Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule

Sickle cell disease is an autosomal recessive genetic red cell disorder with a worldwide distribution. Growing evidence suggests a possible involvement of complement activation in the severity of clinical complications of sickle cell disease. In this study we found activation of the alternative comp...

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Detalles Bibliográficos
Autores principales: Lombardi, Elisabetta, Matte, Alessandro, Risitano, Antonio M., Ricklin, Daniel, Lambris, John D., De Zanet, Denise, Jokiranta, Sakari T., Martinelli, Nicola, Scambi, Cinzia, Salvagno, Gianluca, Bisoffi, Zeno, Colato, Chiara, Siciliano, Angela, Bortolami, Oscar, Mazzuccato, Mario, Zorzi, Francesco, De Marco, Luigi, De Franceschi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518911/
https://www.ncbi.nlm.nih.gov/pubmed/30630982
http://dx.doi.org/10.3324/haematol.2018.198622

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