Cargando…

Dual‐specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis

The Ras/mitogen‐activated protein kinase (MAPK) pathway controls fundamental cellular processes such as proliferation, differentiation, and apoptosis. The dual‐specificity phosphatase 6 (DUSP6) regulates cytoplasmic MAPK signaling by dephosphorylating and inactivating extracellular signal‐regulated...

Descripción completa

Detalles Bibliográficos
Autores principales: Beaudry, Katia, Langlois, Marie‐Josée, Montagne, Amélie, Cagnol, Sébastien, Carrier, Julie C., Rivard, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519001/
https://www.ncbi.nlm.nih.gov/pubmed/30273442
http://dx.doi.org/10.1002/jcp.27420