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Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG

The major facilitator superfamily transporter Rv1410 and the lipoprotein LprG (Rv1411) are encoded by a conserved two‐gene operon and contribute to virulence in Mycobacterium tuberculosis. Rv1410 was originally postulated to function as a drug efflux pump, but recent studies suggested that Rv1410 an...

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Detalles Bibliográficos
Autores principales: Hohl, Michael, Remm, Sille, Eskandarian, Haig A., Dal Molin, Michael, Arnold, Fabian M., Hürlimann, Lea M., Krügel, Andri, Fantner, Georg E., Sander, Peter, Seeger, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519032/
https://www.ncbi.nlm.nih.gov/pubmed/30742339
http://dx.doi.org/10.1111/mmi.14220