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Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG
The major facilitator superfamily transporter Rv1410 and the lipoprotein LprG (Rv1411) are encoded by a conserved two‐gene operon and contribute to virulence in Mycobacterium tuberculosis. Rv1410 was originally postulated to function as a drug efflux pump, but recent studies suggested that Rv1410 an...
Autores principales: | Hohl, Michael, Remm, Sille, Eskandarian, Haig A., Dal Molin, Michael, Arnold, Fabian M., Hürlimann, Lea M., Krügel, Andri, Fantner, Georg E., Sander, Peter, Seeger, Markus A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519032/ https://www.ncbi.nlm.nih.gov/pubmed/30742339 http://dx.doi.org/10.1111/mmi.14220 |
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