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Comparative study of cerebrospinal fluid α‐synuclein seeding aggregation assays for diagnosis of Parkinson's disease

BACKGROUND: PD diagnosis is based primarily on clinical criteria and can be inaccurate. Biological markers, such as α‐synuclein aggregation, that reflect ongoing pathogenic processes may increase diagnosis accuracy and allow disease progression monitoring. Though α‐synuclein aggregation assays have...

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Detalles Bibliográficos
Autores principales: Kang, Un Jung, Boehme, Amelia K., Fairfoul, Graham, Shahnawaz, Mohammad, Ma, Thong Chi, Hutten, Samantha J., Green, Alison, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519150/
https://www.ncbi.nlm.nih.gov/pubmed/30840785
http://dx.doi.org/10.1002/mds.27646