A Phase 1 Randomized Study of Single Intravenous Infusions of the Novel Nitroxyl Donor BMS‐986231 in Healthy Volunteers

Nitroxyl (HNO) is a reactive nitrogen molecule that has potential therapeutic benefits for patients with acute heart failure. The results of the first‐in‐human study for BMS‐986231, a novel HNO donor, are reported. The aim of this sequential cohort study was to evaluate the safety, tolerability, and...

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Detalles Bibliográficos
Autores principales: Cowart, Douglas, Venuti, Robert P., Lynch, Kim, Guptill, Jeffrey T., Noveck, Robert J., Foo, Shi Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519195/
https://www.ncbi.nlm.nih.gov/pubmed/30703258
http://dx.doi.org/10.1002/jcph.1364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519195/
https://www.ncbi.nlm.nih.gov/pubmed/30703258
http://dx.doi.org/10.1002/jcph.1364

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