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The tyrosine phosphatase Shp‐2 confers resistance to colonic inflammation by driving goblet cell function and crypt regeneration
The Src homology‐2 domain‐containing tyrosine phosphatase 2 (SHP‐2) regulates many cellular processes, including proliferation, differentiation and survival. Polymorphisms in the gene encoding SHP‐2 are associated with an increased susceptibility to develop ulcerative colitis. We recently reported t...
Autores principales: | Gagné‐Sansfacon, Jessica, Langlois, Ariane, Langlois, Marie‐Josée, Coulombe, Geneviève, Tremblay, Sarah, Vaillancourt‐Lavigueur, Vanessa, Qu, Cheng‐Kui, Menendez, Alfredo, Rivard, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519201/ https://www.ncbi.nlm.nih.gov/pubmed/30376595 http://dx.doi.org/10.1002/path.5177 |
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