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Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm

BACKGROUND: Case series and a post hoc subgroup analysis of a large randomized trial have suggested a potential benefit in treating ruptured abdominal aortic aneurysms (rAAAs) using endovascular aneurysm repair (EVAR) with local anaesthesia (LA) rather than general anaesthesia (GA). The uptake and o...

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Autores principales: Mouton, R., Rogers, C. A., Harris, R. A., Hinchliffe, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519219/
https://www.ncbi.nlm.nih.gov/pubmed/30136715
http://dx.doi.org/10.1002/bjs.10973
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author Mouton, R.
Rogers, C. A.
Harris, R. A.
Hinchliffe, R. J.
author_facet Mouton, R.
Rogers, C. A.
Harris, R. A.
Hinchliffe, R. J.
author_sort Mouton, R.
collection PubMed
description BACKGROUND: Case series and a post hoc subgroup analysis of a large randomized trial have suggested a potential benefit in treating ruptured abdominal aortic aneurysms (rAAAs) using endovascular aneurysm repair (EVAR) with local anaesthesia (LA) rather than general anaesthesia (GA). The uptake and outcomes of LA in clinical practice remain unknown. METHODS: The UK National Vascular Registry was interrogated for patients presenting with rAAA managed with EVAR under different modes of anaesthesia between 1 January 2014 and 31 December 2016. The primary outcome was in‐hospital mortality. Secondary outcomes included: the number of centres performing EVAR under LA; the proportion of patients receiving this technique; duration of hospital stay; and postoperative complications. RESULTS: Some 3101 patients with rAAA were treated in 72 hospitals during the study: 2306 underwent on open procedure and 795 had EVAR (LA, 319; GA, 435; regional anaesthesia, 41). Overall, 56 of 72 hospitals (78 per cent) offered LA for EVAR of rAAA. Baseline characteristics and morphology were similar across the three EVAR subgroups. Patients who had surgery under LA had a lower in‐hospital mortality rate than patients who received GA (59 of 319 (18·5 per cent) versus 122 of 435 (28·0 per cent)), and this was unchanged after adjustment for factors known to influence survival (adjusted hazard ratio 0·62, 95 per cent c.i. 0·45 to 0·85; P = 0·003). Median hospital stay and postoperative morbidity from other complications were similar. CONCLUSION: The use of LA for EVAR of rAAA has been adopted widely in the UK. Mortality rates appear lower than in patients undergoing EVAR with GA.
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spelling pubmed-65192192019-05-21 Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm Mouton, R. Rogers, C. A. Harris, R. A. Hinchliffe, R. J. Br J Surg Original Articles BACKGROUND: Case series and a post hoc subgroup analysis of a large randomized trial have suggested a potential benefit in treating ruptured abdominal aortic aneurysms (rAAAs) using endovascular aneurysm repair (EVAR) with local anaesthesia (LA) rather than general anaesthesia (GA). The uptake and outcomes of LA in clinical practice remain unknown. METHODS: The UK National Vascular Registry was interrogated for patients presenting with rAAA managed with EVAR under different modes of anaesthesia between 1 January 2014 and 31 December 2016. The primary outcome was in‐hospital mortality. Secondary outcomes included: the number of centres performing EVAR under LA; the proportion of patients receiving this technique; duration of hospital stay; and postoperative complications. RESULTS: Some 3101 patients with rAAA were treated in 72 hospitals during the study: 2306 underwent on open procedure and 795 had EVAR (LA, 319; GA, 435; regional anaesthesia, 41). Overall, 56 of 72 hospitals (78 per cent) offered LA for EVAR of rAAA. Baseline characteristics and morphology were similar across the three EVAR subgroups. Patients who had surgery under LA had a lower in‐hospital mortality rate than patients who received GA (59 of 319 (18·5 per cent) versus 122 of 435 (28·0 per cent)), and this was unchanged after adjustment for factors known to influence survival (adjusted hazard ratio 0·62, 95 per cent c.i. 0·45 to 0·85; P = 0·003). Median hospital stay and postoperative morbidity from other complications were similar. CONCLUSION: The use of LA for EVAR of rAAA has been adopted widely in the UK. Mortality rates appear lower than in patients undergoing EVAR with GA. John Wiley & Sons, Ltd 2018-08-23 2019-01 /pmc/articles/PMC6519219/ /pubmed/30136715 http://dx.doi.org/10.1002/bjs.10973 Text en © 2018 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Mouton, R.
Rogers, C. A.
Harris, R. A.
Hinchliffe, R. J.
Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
title Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
title_full Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
title_fullStr Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
title_full_unstemmed Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
title_short Local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
title_sort local anaesthesia for endovascular repair of ruptured abdominal aortic aneurysm
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519219/
https://www.ncbi.nlm.nih.gov/pubmed/30136715
http://dx.doi.org/10.1002/bjs.10973
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AT hinchlifferj localanaesthesiaforendovascularrepairofrupturedabdominalaorticaneurysm