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Selective remodeling of glutamatergic transmission to striatal cholinergic interneurons after dopamine depletion

The widely held view that the pathophysiology of Parkinson's disease arises from an under‐activation of the direct pathway striatal spiny neurons (dSPNs) has gained support from a recently described weakening of the glutamatergic projection from the parafascicular nucleus (PfN) to dSPNs in expe...

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Detalles Bibliográficos
Autores principales: Aceves Buendia, Jose de Jesus, Tiroshi, Lior, Chiu, Wei‐Hua, Goldberg, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519226/
https://www.ncbi.nlm.nih.gov/pubmed/28922504
http://dx.doi.org/10.1111/ejn.13715