Cargando…

HLA class II expression on tumor cells and low numbers of tumor‐associated macrophages predict clinical outcome in oropharyngeal cancer

BACKGROUND: Human papillomavirus (HPV)‐positive oropharyngeal squamous cell carcinoma (OPSCC) is a highly immunogenic tumor and differences in tumor microenvironment might contribute to the improved survival of HPV‐positive OPSCC patient. METHODS: A comprehensive multivariate analysis with clinical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cioni, Bianca, Jordanova, Ekaterina S., Hooijberg, Erik, van der Linden, Rianne, de Menezes, Renee X., Tan, Katherine, Willems, Stefan, Elbers, Joris B. W., Broeks, Annegien, Bergman, Andries M., Zuur, Charlotte L., de Boer, Jan Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519285/ https://www.ncbi.nlm.nih.gov/pubmed/30549362 http://dx.doi.org/10.1002/hed.25442

Ejemplares similares

Distinct Patterns of Myeloid Cell Infiltration in Patients With hrHPV-Positive and hrHPV-Negative Penile Squamous Cell Carcinoma: The Importance of Assessing Myeloid Cell Densities Within the Spatial Context of the Tumor
por: Rafael, Tynisha S., et al.
Publicado: (2021)

Sponge-supported cultures of primary head and neck tumors for an optimized preclinical model
por: Dohmen, Amy J.C., et al.
Publicado: (2018)

Neoadjuvant cisplatin and paclitaxel modulate tumor-infiltrating T cells in patients with cervical cancer
por: Heeren, A. Marijne, et al.
Publicado: (2019)

A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency
por: Punt, Simone, et al.
Publicado: (2016)

HLA Class I and II Expression in Oropharyngeal Squamous Cell Carcinoma in Relation to Tumor HPV Status and Clinical Outcome
por: Näsman, Anders, et al.
Publicado: (2013)

Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses
por: Santegoets, S. J., et al.
Publicado: (2019)

The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer
por: van Dijk, Nick, et al.
Publicado: (2021)

HLA-E expression in cervical adenocarcinomas: association with improved long-term survival
por: Spaans, Vivian M, et al.
Publicado: (2012)

Warthin tumor of the oropharyngeal minor salivary gland
por: Diaz-Segarra, Nicole, et al.
Publicado: (2018)

Unlocking the therapeutic potential of primary tumor-draining lymph nodes
por: Rotman, Jossie, et al.
Publicado: (2019)

Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma
por: Mehta, Akash M., et al.
Publicado: (2007)

Transoral reconstruction of oropharyngeal tumors. The Hospital Clínic algorithm
por: Avilés-Jurado, Francesc Xavier, et al.
Publicado: (2020)

The Tumor Microenvironment and Immunotherapy of Oropharyngeal Squamous Cell Carcinoma
por: Welters, Marij J. P., et al.
Publicado: (2020)

A concealed giant peritonsillolith masquerading as oropharyngeal tumor()
por: Gan, Boon Chye, et al.
Publicado: (2017)

Loss of androgen receptor signaling in prostate cancer‐associated fibroblasts (CAFs) promotes CCL2‐ and CXCL8‐mediated cancer cell migration
por: Cioni, Bianca, et al.
Publicado: (2018)

Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
por: Cioni, Bianca, et al.
Publicado: (2020)

Beta-Catenin and Epithelial Tumors: A Study Based on 374 Oropharyngeal Cancers
por: Santoro, Angela, et al.
Publicado: (2014)

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma
por: Vos, Joris L., et al.
Publicado: (2021)

Recent advances in managing human papillomavirus-positive oropharyngeal tumors
por: Cantu, Giulio, et al.
Publicado: (2010)

Personalized HLA typing leads to the discovery of novel HLA alleles and tumor‐specific HLA variants
por: Anzar, Irantzu, et al.
Publicado: (2022)

Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy
por: Li, Xiangyong, et al.
Publicado: (2021)

HLA-G Neo-Expression on Tumors
por: Loustau, Maria, et al.
Publicado: (2020)

Tumor PD-L1 status and CD8(+) tumor-infiltrating T cells: markers of improved prognosis in oropharyngeal cancer
por: De Meulenaere, Astrid, et al.
Publicado: (2017)

Detection of Human Papillomavirus Integration in Brain Metastases from Oropharyngeal Tumors by Targeted Sequencing
por: McEllin, Brian, et al.
Publicado: (2021)

Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases
por: Ferns, Debbie M., et al.
Publicado: (2016)

Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review
por: Dohmen, Amy J. C., et al.
Publicado: (2015)

Analysis of a hit‐and‐run tumor model by HPV in oropharyngeal cancers
por: Ferreira, Danyelle Assis, et al.
Publicado: (2022)

A predictive model for residual disease after (chemo) radiotherapy in oropharyngeal carcinoma: Combined radiological and clinical evaluation of tumor response
por: Gouw, Zeno A.R., et al.
Publicado: (2017)

The adaptive immune system promotes initiation of prostate carcinogenesis in a human c-Myc transgenic mouse model
por: Melis, Monique H.M., et al.
Publicado: (2017)

Survival and quality of life of patients with oral and oropharyngeal cancer at 1-year follow-up of tumor resection
por: BIAZEVIC, Maria Gabriela Haye, et al.
Publicado: (2010)

A Review of the Effects of Cervical Cancer Standard Treatment on Immune Parameters in Peripheral Blood, Tumor Draining Lymph Nodes, and Local Tumor Microenvironment
por: van Luijk, Iske F., et al.
Publicado: (2022)

Identification of Tumor Antigens in the HLA Peptidome of Patient-derived Xenograft Tumors in Mouse
por: Rijensky, Nataly Mancette, et al.
Publicado: (2020)

HPV-associated differential regulation of tumor metabolism in oropharyngeal head and neck cancer
por: Jung, Young-Suk, et al.
Publicado: (2017)

Tumor and Nodal Disease Growth Rates in Patients with Oropharyngeal Squamous Cell Carcinoma
por: Farber, Nicole I., et al.
Publicado: (2023)

Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control
por: Johanna, Inez, et al.
Publicado: (2021)

Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
por: Castro, Andrea, et al.
Publicado: (2019)

Pervasiveness of HLA allele-specific expression loss across tumor types
por: Filip, Ioan, et al.
Publicado: (2023)

Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition
por: Rao, Xiangyu, et al.
Publicado: (2013)

Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk
por: Almekinders, Mathilde M., et al.
Publicado: (2022)

The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination
por: Mühlenbruch, Lena, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jv9n72gpqj16c8fddu4osresvf