Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation

Distant metastatic disease from gliomas is extremely rare. We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. The presence of an H3F3A mutation in these p...

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Autores principales: Jethanandani, Amit, Gule-Monroe, Maria K., Chen, Melissa, Johnson, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519298/
https://www.ncbi.nlm.nih.gov/pubmed/31139567
http://dx.doi.org/10.3389/fonc.2019.00373
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author Jethanandani, Amit
Gule-Monroe, Maria K.
Chen, Melissa
Johnson, Jason M.
author_facet Jethanandani, Amit
Gule-Monroe, Maria K.
Chen, Melissa
Johnson, Jason M.
author_sort Jethanandani, Amit
collection PubMed
description Distant metastatic disease from gliomas is extremely rare. We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. The presence of an H3F3A mutation in these patients may indicate further work-up to include intensive staging examination.
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spelling pubmed-65192982019-05-28 Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation Jethanandani, Amit Gule-Monroe, Maria K. Chen, Melissa Johnson, Jason M. Front Oncol Oncology Distant metastatic disease from gliomas is extremely rare. We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation. The presence of an H3F3A mutation in these patients may indicate further work-up to include intensive staging examination. Frontiers Media S.A. 2019-05-08 /pmc/articles/PMC6519298/ /pubmed/31139567 http://dx.doi.org/10.3389/fonc.2019.00373 Text en Copyright © 2019 Jethanandani, Gule-Monroe, Chen and Johnson. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Jethanandani, Amit
Gule-Monroe, Maria K.
Chen, Melissa
Johnson, Jason M.
Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation
title Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation
title_full Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation
title_fullStr Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation
title_full_unstemmed Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation
title_short Extraneural Metastases From a High-Grade Glioma (HGG) With an H3F3A G34R Mutation
title_sort extraneural metastases from a high-grade glioma (hgg) with an h3f3a g34r mutation
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519298/
https://www.ncbi.nlm.nih.gov/pubmed/31139567
http://dx.doi.org/10.3389/fonc.2019.00373
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