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Non-invasive Motor Cortex Neuromodulation Reduces Secondary Hyperalgesia and Enhances Activation of the Descending Pain Modulatory Network
Central sensitization is a driving mechanism in many chronic pain patients, and manifests as hyperalgesia and allodynia beyond any apparent injury. Recent studies have demonstrated analgesic effects of motor cortex (M1) stimulation in several chronic pain disorders, yet its neural mechanisms remain...
Autores principales: | Meeker, Timothy J., Keaser, Michael L., Khan, Shariq A., Gullapalli, Rao P., Seminowicz, David A., Greenspan, Joel D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519323/ https://www.ncbi.nlm.nih.gov/pubmed/31139047 http://dx.doi.org/10.3389/fnins.2019.00467 |
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