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Modeling Host-Pathogen Interaction to Elucidate the Metabolic Drug Response of Intracellular Mycobacterium tuberculosis

Little is known about the metabolic state of Mycobacterium tuberculosis (Mtb) inside the phagosome, a compartment inside phagocytes for killing pathogens and other foreign substances. We have developed a combined model of Mtb and human metabolism, sMtb-RECON and used this model to predict the metabo...

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Detalles Bibliográficos
Autores principales:	Rienksma, Rienk A., Schaap, Peter J., Martins dos Santos, Vitor A. P., Suarez-Diez, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519342/ https://www.ncbi.nlm.nih.gov/pubmed/31139575 http://dx.doi.org/10.3389/fcimb.2019.00144

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