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Lugdunomycin, an Angucycline‐Derived Molecule with Unprecedented Chemical Architecture
The angucyclines form the largest family of polycyclic aromatic polyketides, and have been studied extensively. Herein, we report the discovery of lugdunomycin, an angucycline‐derived polyketide, produced by Streptomyces species QL37. Lugdunomycin has unique structural characteristics, including a h...
Autores principales: | Wu, Changsheng, van der Heul, Helga U., Melnik, Alexey V., Lübben, Jens, Dorrestein, Pieter C., Minnaard, Adriaan J., Choi, Young Hae, van Wezel, Gilles P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519343/ https://www.ncbi.nlm.nih.gov/pubmed/30656821 http://dx.doi.org/10.1002/anie.201814581 |
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