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Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013

OBJECTIVES: To describe changes in mortality among patients undergoing coronary artery bypass grafting (CABG) in New South Wales (NSW) Australia from 2000 to 2013. METHODS: Patients undergoing CABG were identified from the NSW Admission Patient Data Collection (APDC) registry, linked to the NSW stat...

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Autores principales: Brieger, David B, Ng, Austin C C, Chow, Vincent, D'Souza, Mario, Hyun, Karice, Bannon, Paul G, Kritharides, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519410/
https://www.ncbi.nlm.nih.gov/pubmed/31168375
http://dx.doi.org/10.1136/openhrt-2018-000959
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author Brieger, David B
Ng, Austin C C
Chow, Vincent
D'Souza, Mario
Hyun, Karice
Bannon, Paul G
Kritharides, Leonard
author_facet Brieger, David B
Ng, Austin C C
Chow, Vincent
D'Souza, Mario
Hyun, Karice
Bannon, Paul G
Kritharides, Leonard
author_sort Brieger, David B
collection PubMed
description OBJECTIVES: To describe changes in mortality among patients undergoing coronary artery bypass grafting (CABG) in New South Wales (NSW) Australia from 2000 to 2013. METHODS: Patients undergoing CABG were identified from the NSW Admission Patient Data Collection (APDC) registry, linked to the NSW state-wide death registry database. Changes in all-cause mortality over time were observed following stratification of the study cohort into two year groups. RESULTS: We identified 54 767 patients undergoing CABG during the study period. The risk profile of patients increased over time with significant increases in age, comorbidities and concomitant valve surgery (all p < 0.0001). During a median follow-up period of 6 years, a total 12 161 (22.2%) of patients had died. Survival curves and adjusted analyses showed a steady fall in mortality rate: those operated on during 2012–2013 had 40 % lower mortality than those operated on during 2000–2001 (HR 0.61; 95% CI 0.53 to 0.69). This was contributed to both by a fall in mortality both in hospital (HR 0.48, 95% CI 0.37 to 0.62) and postdischarge (HR 0.73; 95% CI 0.61 to 0.86). CONCLUSIONS: We report a consistent reduction in medium-term mortality among a large unselected cohort of NSW patients undergoing CABG between 2000 and 2013. This fall is attributable both to an improvement in outcomes in hospital and in the postdischarge period.
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spelling pubmed-65194102019-06-05 Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013 Brieger, David B Ng, Austin C C Chow, Vincent D'Souza, Mario Hyun, Karice Bannon, Paul G Kritharides, Leonard Open Heart Cardiac Surgery OBJECTIVES: To describe changes in mortality among patients undergoing coronary artery bypass grafting (CABG) in New South Wales (NSW) Australia from 2000 to 2013. METHODS: Patients undergoing CABG were identified from the NSW Admission Patient Data Collection (APDC) registry, linked to the NSW state-wide death registry database. Changes in all-cause mortality over time were observed following stratification of the study cohort into two year groups. RESULTS: We identified 54 767 patients undergoing CABG during the study period. The risk profile of patients increased over time with significant increases in age, comorbidities and concomitant valve surgery (all p < 0.0001). During a median follow-up period of 6 years, a total 12 161 (22.2%) of patients had died. Survival curves and adjusted analyses showed a steady fall in mortality rate: those operated on during 2012–2013 had 40 % lower mortality than those operated on during 2000–2001 (HR 0.61; 95% CI 0.53 to 0.69). This was contributed to both by a fall in mortality both in hospital (HR 0.48, 95% CI 0.37 to 0.62) and postdischarge (HR 0.73; 95% CI 0.61 to 0.86). CONCLUSIONS: We report a consistent reduction in medium-term mortality among a large unselected cohort of NSW patients undergoing CABG between 2000 and 2013. This fall is attributable both to an improvement in outcomes in hospital and in the postdischarge period. BMJ Publishing Group 2019-03-30 /pmc/articles/PMC6519410/ /pubmed/31168375 http://dx.doi.org/10.1136/openhrt-2018-000959 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Cardiac Surgery
Brieger, David B
Ng, Austin C C
Chow, Vincent
D'Souza, Mario
Hyun, Karice
Bannon, Paul G
Kritharides, Leonard
Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013
title Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013
title_full Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013
title_fullStr Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013
title_full_unstemmed Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013
title_short Falling hospital and postdischarge mortality following CABG in New South Wales from 2000 to 2013
title_sort falling hospital and postdischarge mortality following cabg in new south wales from 2000 to 2013
topic Cardiac Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519410/
https://www.ncbi.nlm.nih.gov/pubmed/31168375
http://dx.doi.org/10.1136/openhrt-2018-000959
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