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A case of aortitis during cisplatin-based chemotherapy for cervical cancer

A case of aortitis in a patient undergoing adjuvant cisplatin and topotecan chemotherapy for cervical cancer following presentation with pyrexia of unknown origin and raised inflammatory markers is presented. Although many chemotherapy agents are known to cause small vessel vasculitis and there are...

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Detalles Bibliográficos
Autores principales: Webb, Katharine, Prakash, Vineet, Kirresh, Othman, Stewart, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519499/
https://www.ncbi.nlm.nih.gov/pubmed/31131127
http://dx.doi.org/10.1259/bjrcr.20180054
Descripción
Sumario:A case of aortitis in a patient undergoing adjuvant cisplatin and topotecan chemotherapy for cervical cancer following presentation with pyrexia of unknown origin and raised inflammatory markers is presented. Although many chemotherapy agents are known to cause small vessel vasculitis and there are several reported cases of large vessel vasculitis following gemcitabine chemotherapy, there is only one previously described case of aortitis following cisplatin administration. This case is presented with corresponding CT and (18)F-FDG PET-CT imaging with discussion of the literature regarding vasculitis and chemotherapy.