Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70

The J-domain protein Zuotin is a multi-domain eukaryotic Hsp70 co-chaperone. Though it is primarily ribosome-associated, positioned at the exit of the 60S subunit tunnel where it promotes folding of nascent polypeptide chains, Zuotin also has off-ribosome functions. Domains of Zuotin needed for 60S...

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Detalles Bibliográficos
Autores principales: Shrestha, Om Kumar, Sharma, Ruchika, Tomiczek, Bartlomiej, Lee, Woonghee, Tonelli, Marco, Cornilescu, Gabriel, Stolarska, Milena, Nierzwicki, Lukasz, Czub, Jacek, Markley, John L., Marszalek, Jaroslaw, Ciesielski, Szymon J., Craig, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519820/
https://www.ncbi.nlm.nih.gov/pubmed/31091298
http://dx.doi.org/10.1371/journal.pone.0217098

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