Functional robustness of adult spermatogonial stem cells after induction of hyperactive Hras

Accumulating evidence indicates that paternal age correlates with disease risk in children. De novo gain-of-function mutations in the FGF-RAS-MAPK signaling pathway are known to cause a subset of genetic diseases associated with advanced paternal age, such as Apert syndrome, achondroplasia, Noonan s...

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Detalles Bibliográficos
Autores principales: Yamada, Makiko, Cai, Winson, Martin, Laura A., N’Tumba-Byn, Thierry, Seandel, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519842/
https://www.ncbi.nlm.nih.gov/pubmed/31050682
http://dx.doi.org/10.1371/journal.pgen.1008139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519842/
https://www.ncbi.nlm.nih.gov/pubmed/31050682
http://dx.doi.org/10.1371/journal.pgen.1008139

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