Cargando…

Resveratrol prevents sarcopenic obesity by reversing mitochondrial dysfunction and oxidative stress via the PKA/LKB1/AMPK pathway

Background: The concept of sarcopenic obesity refers to low muscle mass coupled with high adiposity in older adults. Sarcopenic obesity is a new medical challenge that imposes tremendous financial burdens on healthcare authorities worldwide. This study investigated the effects of resveratrol on high...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yujie, Zhu, Xiaohui, Chen, Ka, Lang, Hedong, Zhang, Yong, Hou, Pengfei, Ran, Li, Zhou, Min, Zheng, Jiawei, Yi, Long, Mi, Mantian, Zhang, Qianyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519996/ https://www.ncbi.nlm.nih.gov/pubmed/30988232 http://dx.doi.org/10.18632/aging.101910

Ejemplares similares

S-Equol ameliorates insulin secretion failure through Chrebp/Txnip signaling via modulating PKA/PP2A activities
por: Chen, Ka, et al.
Publicado: (2020)

LKB1/AMPK and PKA Control ABCB11 Trafficking and Polarization in Hepatocytes
por: Homolya, László, et al.
Publicado: (2014)

PKA Activates AMPK Through LKB1 Signaling in Follicular Thyroid Cancer
por: Kari, Suresh, et al.
Publicado: (2019)

Liquiritin Attenuates Pathological Cardiac Hypertrophy by Activating the PKA/LKB1/AMPK Pathway
por: Aiyasiding, Xiahenazi, et al.
Publicado: (2022)

Long-term high loading intensity of aerobic exercise improves skeletal muscle performance via the gut microbiota-testosterone axis
por: Zhang, Lidong, et al.
Publicado: (2022)

Dihydromyricetin-Encapsulated Liposomes Inhibit Exhaustive Exercise-Induced Liver Inflammation by Orchestrating M1/M2 Macrophage Polarization
por: Zhou, Xi, et al.
Publicado: (2022)

Dihydromyricetin Enhances Exercise-Induced GLP-1 Elevation through Stimulating cAMP and Inhibiting DPP-4
por: Wu, Luting, et al.
Publicado: (2022)

Dihydromyricetin Protects Intestinal Barrier Integrity by Promoting IL-22 Expression in ILC3s through the AMPK/SIRT3/STAT3 Signaling Pathway
por: Zhou, Jie, et al.
Publicado: (2023)

Pterostilbene Enhances Endurance Capacity via Promoting Skeletal Muscle Adaptations to Exercise Training in Rats
por: Zheng, Jiawei, et al.
Publicado: (2020)

AMPK potentiation by LKB1 isoforms
por: Thibert, Chantal, et al.
Publicado: (2015)

Ampelopsin Improves Insulin Resistance by Activating PPARγ and Subsequently Up-Regulating FGF21-AMPK Signaling Pathway
por: Zhou, Yong, et al.
Publicado: (2016)

LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis
por: Qu, Shuang, et al.
Publicado: (2022)

Connecting LKB1 and AMPK links metabolism with cancer
por: Moore, Pete
Publicado: (2003)

MLK3 Phophorylates AMPK Independently of LKB1
por: Luo, Lingyu, et al.
Publicado: (2015)

Synergistic antitumor effect of resveratrol and sorafenib on hepatocellular carcinoma through PKA/AMPK/eEF2K pathway
por: Gao, Meili, et al.
Publicado: (2021)

Dihydromyricetin Attenuates High-Intensity Exercise-Induced Intestinal Barrier Dysfunction Associated with the Modulation of the Phenotype of Intestinal Intraepithelial Lymphocytes
por: Hou, Pengfei, et al.
Publicado: (2022)

Hepatic PKA inhibition accelerates the lipid accumulation in liver
por: Yang, Jining, et al.
Publicado: (2019)

Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down‐regulation of phosphorylation of PPARγ in 3T3‐L1 cells
por: Liu, Lei, et al.
Publicado: (2017)

Arsenic Inhibits Neurite Outgrowth by Inhibiting the LKB1–AMPK Signaling Pathway
por: Wang, Xin, et al.
Publicado: (2010)

LKB1 and AMPK and the cancer-metabolism link - ten years after
por: Hardie, D Grahame, et al.
Publicado: (2013)

LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK
por: Jeppesen, Jacob, et al.
Publicado: (2013)

LKB1 and AMPK differentially regulate pancreatic β-cell identity
por: Kone, Marina, et al.
Publicado: (2014)

A subset of VEGFR‐TKIs activates AMPK in LKB1‐mutant lung cancer
por: Yang, Lujie, et al.
Publicado: (2022)

Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells
por: Zhang, Ting, et al.
Publicado: (2016)

LKB1-AMPK axis negatively regulates ferroptosis by inhibiting fatty acid synthesis
por: Li, Changzhi, et al.
Publicado: (2020)

Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism
por: Huang, Yuanyuan, et al.
Publicado: (2021)

MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis
por: Hui, Chang, et al.
Publicado: (2012)

LKB1 and AMPK maintain epithelial cell polarity under energetic stress
por: Mirouse, Vincent, et al.
Publicado: (2007)

LKB1 and AMPK maintain epithelial cell polarity under energetic stress
por: Mirouse, Vincent, et al.
Publicado: (2013)

LKB1/AMPK Pathway and Drug Response in Cancer: A Therapeutic Perspective
por: Ciccarese, Francesco, et al.
Publicado: (2019)

LKB1 and AMPK instruct cone nuclear position to modify visual function
por: Burger, Courtney A., et al.
Publicado: (2021)

Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation
por: Rho, Seung Bae, et al.
Publicado: (2021)

PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1
por: Mung, Kwan Long, et al.
Publicado: (2021)

Flavonoids, Flavonoid Subclasses and Breast Cancer Risk: A Meta-Analysis of Epidemiologic Studies
por: Hui, Chang, et al.
Publicado: (2013)

3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation
por: Peng, Xiaoli, et al.
Publicado: (2017)

Comparative effects of different whole grains and brans on blood lipid: a network meta-analysis
por: Hui, Suocheng, et al.
Publicado: (2018)

Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling
por: Li, Nan, et al.
Publicado: (2019)

Beneficial Effect of Taraxacum coreanum Nakai via the Activation of LKB1-AMPK Signaling Pathway on Obesity
por: Shin, Mi-Rae, et al.
Publicado: (2021)

Resveratrol attenuates endothelial oxidative injury by inducing autophagy via the activation of transcription factor EB
por: Zhou, Xi, et al.
Publicado: (2019)

Myricetin improves endurance capacity by inducing muscle fiber type conversion via miR-499
por: Wu, Luting, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qpeb65n7pbd1vjadhlc276plpo