Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes

Polycomb repressive complexes are evolutionarily conserved complexes that maintain transcriptional repression during development and differentiation to establish and preserve cell identity. We recently described the fundamental role of PRC1 in preserving intestinal stem cell identity through the inh...

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Detalles Bibliográficos
Autores principales: Pivetti, Silvia, Fernandez-Perez, Daniel, D’Ambrosio, Alessandro, Barbieri, Caterina Maria, Manganaro, Daria, Rossi, Alessandra, Barnabei, Laura, Zanotti, Marika, Scelfo, Andrea, Chiacchiera, Fulvio, Pasini, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520019/
https://www.ncbi.nlm.nih.gov/pubmed/31106267
http://dx.doi.org/10.1126/sciadv.aav1594

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