Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Healthy Chinese Subjects

BACKGROUND AND OBJECTIVES: The recombinant human interleukin-1 receptor antagonist (rhIL-1Ra) GR007 is a candidate drug with the potential to prevent the toxicity induced by chemotherapy agents by blocking the IL-1 signaling pathway. The aim of this study was to assess the pharmacokinetics and safet...

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Detalles Bibliográficos
Autores principales: Xie, Ran, Zhang, Yang, Zhao, Nan, Zhou, Shuang, Wang, Xin, Han, Wei, Yu, Yan, Zhao, Xia, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520324/
https://www.ncbi.nlm.nih.gov/pubmed/30382491
http://dx.doi.org/10.1007/s13318-018-0523-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520324/
https://www.ncbi.nlm.nih.gov/pubmed/30382491
http://dx.doi.org/10.1007/s13318-018-0523-5

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