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Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Through combined genetic, in silico, in vitro, and ex vivo approaches, we define CXorf21, a gene of hitherto unk...

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Detalles Bibliográficos
Autores principales:	Odhams, Christopher A., Roberts, Amy L., Vester, Susan K., Duarte, Carolina S. T., Beales, Charlie T., Clarke, Alexander J., Lindinger, Sonja, Daffern, Samuel J., Zito, Antonino, Chen, Lingyan, Jones, Leonardo L., Boteva, Lora, Morris, David L., Small, Kerrin S., Fernando, Michelle M. A., Cunninghame Graham, Deborah S., Vyse, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520347/ https://www.ncbi.nlm.nih.gov/pubmed/31092820 http://dx.doi.org/10.1038/s41467-019-10106-2

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