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Vitamin D3 constrains estrogen’s effects and influences mammary epithelial organization in 3D cultures

Vitamin D3 (vitD3) and its active metabolite, calcitriol (1,25-(OH)(2)D(3)), affect multiple tissue types by interacting with the vitamin D receptor (VDR). Although vitD3 deficiency has been correlated with increased incidence of breast cancer and less favorable outcomes, randomized clinical trials...

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Detalles Bibliográficos
Autores principales: Hasan, Nafis, Sonnenschein, Carlos, Soto, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520380/
https://www.ncbi.nlm.nih.gov/pubmed/31092845
http://dx.doi.org/10.1038/s41598-019-43308-1

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