Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae

Paramyxoviruses and pneumoviruses have similar life cycles and share the respiratory tract as a point of entry. In comparative genome-scale siRNA screens with wild-type-derived measles, mumps, and respiratory syncytial viruses in A549 cells, a human lung adenocarcinoma cell line, we identified vesic...

Descripción completa

Detalles Bibliográficos
Autores principales: Anderson, Danielle E., Pfeffermann, Kristin, Kim, So Young, Sawatsky, Bevan, Pearson, James, Kovtun, Mikhail, Corcoran, David L., Krebs, Yvonne, Sigmundsson, Kristmundur, Jamison, Sharon F., Yeo, Zhen Zhen Joanna, Rennick, Linda J., Wang, Lin-Fa, Talbot, Pierre J., Duprex, W. Paul, Garcia-Blanco, Mariano A., von Messling, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520455/
https://www.ncbi.nlm.nih.gov/pubmed/31088929
http://dx.doi.org/10.1128/mBio.00826-19

Ejemplares similares

Ejemplares similares