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Glucagon-Like Peptide-1 Cleavage Product Improves Cognitive Function in a Mouse Model of Down Syndrome

Currently there is no effective therapy available for cognitive impairments in Down syndrome (DS), one of the most prevalent forms of intellectual disability in humans associated with the chromosomes 21 trisomy. Glucagon-like peptide-1 (GLP-1) is an incretin hormone that maintains glucose homeostasi...

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Detalles Bibliográficos
Autores principales: Day, Stephen M., Yang, Wenzhong, Wang, Xin, Stern, Jennifer E., Zhou, Xueyan, Macauley, Shannon L., Ma, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520642/
https://www.ncbi.nlm.nih.gov/pubmed/31040160
http://dx.doi.org/10.1523/ENEURO.0031-19.2019