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Glucagon-Like Peptide-1 Cleavage Product Improves Cognitive Function in a Mouse Model of Down Syndrome
Currently there is no effective therapy available for cognitive impairments in Down syndrome (DS), one of the most prevalent forms of intellectual disability in humans associated with the chromosomes 21 trisomy. Glucagon-like peptide-1 (GLP-1) is an incretin hormone that maintains glucose homeostasi...
Autores principales: | Day, Stephen M., Yang, Wenzhong, Wang, Xin, Stern, Jennifer E., Zhou, Xueyan, Macauley, Shannon L., Ma, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520642/ https://www.ncbi.nlm.nih.gov/pubmed/31040160 http://dx.doi.org/10.1523/ENEURO.0031-19.2019 |
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