Differential Regulation of Syngap1 Translation by FMRP Modulates eEF2 Mediated Response on NMDAR Activity

SYNGAP1, a Synaptic Ras-GTPase activating protein, regulates synapse maturation during a critical developmental window. Heterozygous mutation in SYNGAP1 (SYNGAP1(-/+)) has been shown to cause Intellectual Disability (ID) in children. Recent studies have provided evidence for altered neuronal protein...

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Detalles Bibliográficos
Autores principales: Paul, Abhik, Nawalpuri, Bharti, Shah, Devanshi, Sateesh, Shruthi, Muddashetty, Ravi S., Clement, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520660/
https://www.ncbi.nlm.nih.gov/pubmed/31143100
http://dx.doi.org/10.3389/fnmol.2019.00097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520660/
https://www.ncbi.nlm.nih.gov/pubmed/31143100
http://dx.doi.org/10.3389/fnmol.2019.00097

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