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ccf-mtDNA as a Potential Link Between the Brain and Immune System in Neuro-Immunological Disorders

Fragments of mitochondrial DNA (mtDNA) are released outside the cell and they appear to persist in extracellular fluids as circulating, cell-free, mtDNA (ccf-mtDNA). When compared to nuclear DNA, such a double stranded mtDNA is more resistant to nuclease degradation. In fact, it is stable extracellu...

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Detalles Bibliográficos
Autores principales:	Gambardella, Stefano, Limanaqi, Fiona, Ferese, Rosangela, Biagioni, Francesca, Campopiano, Rosa, Centonze, Diego, Fornai, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520662/ https://www.ncbi.nlm.nih.gov/pubmed/31143191 http://dx.doi.org/10.3389/fimmu.2019.01064

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