Cargando…

Latent Cytomegalovirus Infection in Female Mice Increases Breast Cancer Metastasis

Cytomegalovirus (CMV) infects 40–70% of women, but infection has been reported in >95% of breast cancer patients. We investigated the consequences of these observations by infecting mice with mCMV or a negative control medium for 4 days, 11 days or 10 weeks to establish active, intermediate or la...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Zelei, Tang, Xiaoyun, Meng, Guanmin, Benesch, Matthew G. K., Mackova, Martina, Belon, Ana Paula, Serrano-Lomelin, Jesus, Goping, Ing Swie, Brindley, David N., Hemmings, Denise G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520675/ https://www.ncbi.nlm.nih.gov/pubmed/30934926 http://dx.doi.org/10.3390/cancers11040447

Ejemplares similares

PDGFRα Enhanced Infection of Breast Cancer Cells with Human Cytomegalovirus but Infection of Fibroblasts Increased Prometastatic Inflammation Involving Lysophosphatidate Signaling
por: Yang, Zelei, et al.
Publicado: (2021)

Human Cytomegalovirus Seropositivity and Viral DNA in Breast Tumors Are Associated with Poor Patient Prognosis
por: Yang, Zelei, et al.
Publicado: (2022)

Lysophosphatidate Induces Chemo-Resistance by Releasing Breast Cancer Cells from Taxol-Induced Mitotic Arrest
por: Samadi, Nasser, et al.
Publicado: (2011)

The Rubella Virus Capsid Is an Anti-Apoptotic Protein that Attenuates the Pore-Forming Ability of Bax
por: Ilkow, Carolina S., et al.
Publicado: (2011)

Role of Adipose Tissue-Derived Autotaxin, Lysophosphatidate Signaling, and Inflammation in the Progression and Treatment of Breast Cancer
por: Brindley, David N., et al.
Publicado: (2020)

Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis
por: Yang, Ning, et al.
Publicado: (2017)

BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis
por: Mann, Jasdeep, et al.
Publicado: (2020)

Characterization of the Apoptotic Response Induced by the Cyanine Dye D112: A Potentially Selective Anti-Cancer Compound
por: Yang, Ning, et al.
Publicado: (2015)

The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer
por: Pandya, Vrajesh, et al.
Publicado: (2016)

Regulated Targeting of BAX to Mitochondria
por: Goping, Ing Swie, et al.
Publicado: (1998)

Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax
por: Heibein, Jeffrey A., et al.
Publicado: (2000)

BIK drives an aggressive breast cancer phenotype through sublethal apoptosis and predicts poor prognosis of ER-positive breast cancer
por: Pandya, Vrajesh, et al.
Publicado: (2020)

Autotaxin and Breast Cancer: Towards Overcoming Treatment Barriers and Sequelae
por: Benesch, Matthew G. K., et al.
Publicado: (2020)

Perforin pores in the endosomal membrane trigger release of endocytosed granzyme B to the cytosol of target cells
por: Thiery, Jerome, et al.
Publicado: (2011)

Control of Cytokines in Latent Cytomegalovirus Infection
por: Chinta, Pearley, et al.
Publicado: (2020)

Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis
por: Nakamura, Kimitoshi, et al.
Publicado: (2000)

Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism
por: Mann, Jasdeep, et al.
Publicado: (2019)

Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo
por: Benesch, Matthew G.K., et al.
Publicado: (2016)

Human Cytomegalovirus Manipulation of Latently Infected Cells
por: Sinclair, John H., et al.
Publicado: (2013)

The latent cytomegalovirus decreases telomere length by microcompetition
por: Polansky, Hanan, et al.
Publicado: (2015)

Decreased Lipid Phosphate Phosphatase 1/3 and Increased Lipid Phosphate Phosphatase 2 Expression in the Human Breast Cancer Tumor Microenvironment Promotes Tumor Progression and Immune System Evasion
por: Benesch, Matthew G. K., et al.
Publicado: (2023)

Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression
por: Benesch, Matthew G. K., et al.
Publicado: (2023)

Latent infection of human cytomegalovirus is associated with the development of gastric cancer
por: JIN, JINJI, et al.
Publicado: (2014)

Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein
por: Krishna, B. A., et al.
Publicado: (2017)

Monocytes Latently Infected with Human Cytomegalovirus Evade Neutrophil Killing
por: Elder, Elizabeth, et al.
Publicado: (2019)

Potential Application of TALENs against Murine Cytomegalovirus Latent Infections
por: Chen, Shiu-Jau, et al.
Publicado: (2019)

Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
por: van der Heijden, Yuri F, et al.
Publicado: (2021)

Quantification of T-cell dynamics during latent cytomegalovirus infection in humans
por: van den Berg, Sara P. H., et al.
Publicado: (2021)

BAD regulates mammary gland morphogenesis by 4E-BP1-mediated control of localized translation in mouse and human models
por: Githaka, John Maringa, et al.
Publicado: (2021)

Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization
por: Alanio, Cécile, et al.
Publicado: (2022)

A Single-Cell Approach to the Elusive Latent Human Cytomegalovirus Transcriptome
por: Goodrum, Felicia, et al.
Publicado: (2018)

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection
por: Lemmermann, Niels A. W., et al.
Publicado: (2021)

Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies
por: De Groof, Timo W. M., et al.
Publicado: (2021)

Navigating the Host Cell Response during Entry into Sites of Latent Cytomegalovirus Infection
por: Murray, Matthew J., et al.
Publicado: (2018)

Cytomegalovirus establishes a latent reservoir and triggers long-lasting inflammation in the eye
por: Voigt, Valentina, et al.
Publicado: (2018)

Reactivation of latent Histoplasma and disseminated cytomegalovirus in a returning traveller with ulcerative colitis
por: Lucey, Olivia, et al.
Publicado: (2018)

Gastric Signet-Ring-Cell Adenocarcinoma with Delayed Retroperitoneal Metastasis and Fibrosis
por: Benesch, Matthew G.K., et al.
Publicado: (2022)

Hierarchical and Redundant Lymphocyte Subset Control Precludes Cytomegalovirus Replication during Latent Infection
por: Polić, Bojan, et al.
Publicado: (1998)

Cytomegalovirus causes a latent infection in undifferentiated cells and is activated by induction of cell differentiation
por: Dutko, FJ, et al.
Publicado: (1981)

Cellular defense against latent colonization foiled by human cytomegalovirus UL138 protein
por: Lee, Song Hee, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_r6rsoo561ea43s0qt1dl0v14ni