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New Furanocembranoids from Briareum violaceum
Three new furanocembranoids—briaviodiol F (1) and briaviotriols A (2) and B (3)—along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1–3 were elucidated by using spectroscopic methods. In vitro study demonstrat...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520705/ https://www.ncbi.nlm.nih.gov/pubmed/30959843 http://dx.doi.org/10.3390/md17040214 |
| _version_ | 1783418792098922496 |
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| author | Huang, Pin-Chang Lin, Wen-Sou Peng, Bo-Rong Chang, Yu-Chia Fang, Lee-Shing Li, Guo-Qiang Hwang, Tsong-Long Wen, Zhi-Hong Sung, Ping-Jyun |
| author_facet | Huang, Pin-Chang Lin, Wen-Sou Peng, Bo-Rong Chang, Yu-Chia Fang, Lee-Shing Li, Guo-Qiang Hwang, Tsong-Long Wen, Zhi-Hong Sung, Ping-Jyun |
| author_sort | Huang, Pin-Chang |
| collection | PubMed |
| description | Three new furanocembranoids—briaviodiol F (1) and briaviotriols A (2) and B (3)—along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1–3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides. |
| format | Online Article Text |
| id | pubmed-6520705 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-65207052019-06-03 New Furanocembranoids from Briareum violaceum Huang, Pin-Chang Lin, Wen-Sou Peng, Bo-Rong Chang, Yu-Chia Fang, Lee-Shing Li, Guo-Qiang Hwang, Tsong-Long Wen, Zhi-Hong Sung, Ping-Jyun Mar Drugs Article Three new furanocembranoids—briaviodiol F (1) and briaviotriols A (2) and B (3)—along with a known analogue, briaviodiol A (4), were obtained from a cultured-type octocoral Briareum violaceum. The structures of cembranoids 1–3 were elucidated by using spectroscopic methods. In vitro study demonstrated that compounds 2 and 4 exerted inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW 264.7, a macrophage cell line that originated from a mouse monocyte macrophage, stimulated with lipopolysaccharides. MDPI 2019-04-05 /pmc/articles/PMC6520705/ /pubmed/30959843 http://dx.doi.org/10.3390/md17040214 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Huang, Pin-Chang Lin, Wen-Sou Peng, Bo-Rong Chang, Yu-Chia Fang, Lee-Shing Li, Guo-Qiang Hwang, Tsong-Long Wen, Zhi-Hong Sung, Ping-Jyun New Furanocembranoids from Briareum violaceum |
| title | New Furanocembranoids from Briareum violaceum |
| title_full | New Furanocembranoids from Briareum violaceum |
| title_fullStr | New Furanocembranoids from Briareum violaceum |
| title_full_unstemmed | New Furanocembranoids from Briareum violaceum |
| title_short | New Furanocembranoids from Briareum violaceum |
| title_sort | new furanocembranoids from briareum violaceum |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520705/ https://www.ncbi.nlm.nih.gov/pubmed/30959843 http://dx.doi.org/10.3390/md17040214 |
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