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Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Remdesivir (GS-5734) is a 1′-cyano-substituted adenosine nucleotide analogue prodrug that shows broad-spectrum antiviral activity against several RNA viruses. This compound is currently under clinical development for the treatment of Ebola virus disease (EVD). While antiviral effects have been demon...

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Detalles Bibliográficos
Autores principales:	Tchesnokov, Egor P., Feng, Joy Y., Porter, Danielle P., Götte, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520719/ https://www.ncbi.nlm.nih.gov/pubmed/30987343 http://dx.doi.org/10.3390/v11040326

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