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Upregulation of Complement Factor H by SOCS-1/3–STAT4 in Lung Cancer

Complement factor H (CFH) is a fluid phase regulator of complement proteins and functions to prevent complement attack and immune surveillance. CFH is known to inactivate therapeutic antibody-dependent complement-mediated cellular cytotoxicity. We found that CFH was highly expressed in human lung ca...

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Detalles Bibliográficos
Autores principales: Yoon, Yeon-Hee, Hwang, Hyeon-Ji, Sung, Hye-Jin, Heo, Sun-Hee, Kim, Dong-Sun, Hong, Su-Hyung, Lee, Kang-Hoon, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520728/
https://www.ncbi.nlm.nih.gov/pubmed/30987235
http://dx.doi.org/10.3390/cancers11040471