Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B

Ground glass hepatocytes (GGHs), a histological hallmark of chronic hepatitis B virus (HBV) infection, contain excessive hepatitis surface antigen (HBsAg) in the endoplasmic reticulum (ER), which is linked to unfolded protein response (UPR). The mechanism by which HBV activates UPR has not been full...

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Detalles Bibliográficos
Autores principales: Li, Yao, Xia, Yuchen, Cheng, Xiaoming, Kleiner, David E., Hewitt, Stephen M., Sproch, Julia, Li, Tong, Zhuang, Hui, Liang, T. Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520809/
https://www.ncbi.nlm.nih.gov/pubmed/31027244
http://dx.doi.org/10.3390/v11040386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520809/
https://www.ncbi.nlm.nih.gov/pubmed/31027244
http://dx.doi.org/10.3390/v11040386

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