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Orthotopic Patient-Derived Xenografts of Gastric Cancer to Decipher Drugs Effects on Cancer Stem Cells and Metastatic Dissemination

Gastric cancer is the third leading cause of cancer mortality worldwide. Cancer stem cells (CSC) are at the origin of tumor initiation, chemoresistance, and the formation of metastases. However, there is a lack of mouse models enabling the study of the metastatic process in gastric adenocarcinoma (G...

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Detalles Bibliográficos
Autores principales: Giraud, Julie, Bouriez, Damien, Seeneevassen, Lornella, Rousseau, Benoit, Sifré, Elodie, Giese, Alban, Mégraud, Francis, Lehours, Philippe, Dubus, Pierre, Gronnier, Caroline, Varon, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520896/
https://www.ncbi.nlm.nih.gov/pubmed/31010193
http://dx.doi.org/10.3390/cancers11040560