Cargando…

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

Functions of the GCN5-related N-acetyltransferase (GNAT) family of histone/protein acetyltransferases (HATs) in Foxp3+ T-regulatory (Treg) cells are unexplored, despite the general importance of these enzymes in cell biology. We now show that two prototypical GNAT family members, GCN5 (general contr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yujie, Bao, Chunrong, Wang, Liqing, Han, Rongxiang, Beier, Ulf H., Akimova, Tatiana, Cole, Philip A., Dent, Sharon Y. R., Hancock, Wayne W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520961/ https://www.ncbi.nlm.nih.gov/pubmed/31003455 http://dx.doi.org/10.3390/cancers11040554

Ejemplares similares

HDAC10 deletion promotes Foxp3(+) T-regulatory cell function
por: Dahiya, Satinder, et al.
Publicado: (2020)

Two Lysines in the Forkhead Domain of Foxp3 Are Key to T Regulatory Cell Function
por: Liu, Yujie, et al.
Publicado: (2012)

Inhibition of p300 impairs Foxp3(+) T-regulatory cell function and promotes anti-tumor immunity
por: Liu, Yujie, et al.
Publicado: (2013)

Targeting Sirtuin-1 Alleviates Experimental Autoimmune Colitis by Induction of Foxp3+ T-Regulatory Cells: Sirt1 targeting alleviates autoimmune colitis
por: Akimova, Tatiana, et al.
Publicado: (2014)

A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells
por: Di Giorgio, Eros, et al.
Publicado: (2021)

Posttranslational regulation of the GCN5 and PCAF acetyltransferases
por: Ononye, Onyekachi E., et al.
Publicado: (2022)

Combination of isoform-selective histone/protein deacetylase inhibitors improves Foxp3+ T-regulatory cell function
por: Beier, Ulf H., et al.
Publicado: (2012)

Acetyltransferases GCN5 and PCAF Are Required for B Lymphocyte Maturation in Mice
por: Oksenych, Valentyn, et al.
Publicado: (2021)

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3 + T-regulatory Cell Function and Promotes Antitumor Immunity
por: Wang, Liqing, et al.
Publicado: (2016)

GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action
por: Lew, Qiao Jing, et al.
Publicado: (2014)

Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5
por: Hatakeyama, Dai, et al.
Publicado: (2018)

Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance
por: Jeitany, Maya, et al.
Publicado: (2017)

Helios Expression Is a Marker of T Cell Activation and Proliferation
por: Akimova, Tatiana, et al.
Publicado: (2011)

Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells
por: Koutsogiannouli, Evangelia A., et al.
Publicado: (2017)

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function
por: Huang, Jianbing, et al.
Publicado: (2017)

Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants
por: Wang, Liqing, et al.
Publicado: (2020)

In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5
por: Hatakeyama, Dai, et al.
Publicado: (2021)

Recruitment of Foxp3(+) T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
por: Lee, Iris, et al.
Publicado: (2005)

Resistance of Foxp3+ Regulatory T Cells to Nur77-Induced Apoptosis Promotes Allograft Survival
por: Tao, Ran, et al.
Publicado: (2008)

The p53-HAT connection: PCAF rules?
por: Laptenko, Oleg, et al.
Publicado: (2012)

Discovery of a PCAF Bromodomain Chemical Probe
por: Moustakim, Moses, et al.
Publicado: (2016)

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60
por: Wang, Feng, et al.
Publicado: (2017)

Formulaic language identification model based on GCN fusing associated information
por: Meng, Fanqi, et al.
Publicado: (2022)

Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis
por: Lu, Wei, et al.
Publicado: (2023)

The transcriptional co-activator PCAF regulates cdk2 activity
por: Mateo, Francesca, et al.
Publicado: (2009)

PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway
por: Kong, Chaohua, et al.
Publicado: (2022)

Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3(+) regulatory T cells in humans and mice
por: Bedke, Tanja, et al.
Publicado: (2014)

N-Myc and GCN5 Regulate Significantly Overlapping Transcriptional Programs in Neural Stem Cells
por: Martínez-Cerdeño, Verónica, et al.
Publicado: (2012)

The Effects of Tacrolimus on T-Cell Proliferation Are Short-Lived: A Pilot Analysis of Immune Function Testing
por: Laskin, Benjamin L., et al.
Publicado: (2017)

Three Distinct Domains Contribute to Nuclear Transport of Murine Foxp3
por: Hancock, Wayne W., et al.
Publicado: (2009)

PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription
por: Lew, Qiao Jing, et al.
Publicado: (2011)

PCAF fine‐tunes hepatic metabolic syndrome, inflammatory disease, and cancer
por: Wang, Tongxin, et al.
Publicado: (2018)

PPA-GCN: A Efficient GCN Framework for Prokaryotic Pathways Assignment
por: Lu, Yuntao, et al.
Publicado: (2022)

The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development
por: de Jong, Rob C. M., et al.
Publicado: (2017)

The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma
por: Mittal, Payal, et al.
Publicado: (2020)

Foxp3(+) Regulatory T Cells Promote Lung Epithelial Proliferation
por: Mock, Jason R., et al.
Publicado: (2014)

Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice
por: Mayer, Christian T, et al.
Publicado: (2014)

Coactivators p300 and PCAF physically and functionally interact with the foamy viral trans-activator
por: Bannert, Helmut, et al.
Publicado: (2004)

HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods
por: Quy, Vo Cam, et al.
Publicado: (2012)

Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil()
por: Liu, Tong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tdpb0qharsm4u8jhlm95plc2bp