Local Injection of Submicron Particle Docetaxel is Associated with Tumor Eradication, Reduced Systemic Toxicity and an Immunologic Response in Uro-Oncologic Xenografts

Intratumoral (IT) administration of submicron particle docetaxel (NanoDoce(®), NanOlogy LLC, Fort Worth, TX, USA) and its efficacy against genitourinary-oncologic xenografts in rats and mice, xenograft-site docetaxel concentrations and immune-cell infiltration were studied. IT-NanoDoce(®), IV-doceta...

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Detalles Bibliográficos
Autores principales: Maulhardt, Holly A., Hylle, Lauren, Frost, Michael V., Tornio, Ashley, Dafoe, Sara, Drummond, Leanne, Quinn, David I., Kamat, Ashish M., diZerega, Gere S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520999/
https://www.ncbi.nlm.nih.gov/pubmed/31022918
http://dx.doi.org/10.3390/cancers11040577

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