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Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer

SMURF2, an E3 ubiquitin ligase and suggested tumor suppressor, operates in normal cells to prevent genomic instability and carcinogenesis. However, the mechanisms underlying SMURF2 inactivation in human malignancies remain elusive, as SMURF2 is rarely found mutated or deleted in cancers. We hypothes...

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Detalles Bibliográficos
Autores principales:	Emanuelli, Andrea, Manikoth Ayyathan, Dhanoop, Koganti, Praveen, Shah, Pooja Anil, Apel-Sarid, Liat, Paolini, Biagio, Detroja, Rajesh, Frenkel-Morgenstern, Milana, Blank, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521037/ https://www.ncbi.nlm.nih.gov/pubmed/31003445 http://dx.doi.org/10.3390/cancers11040556

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