Cx43 Expression Correlates with Breast Cancer Metastasis in MDA-MB-231 Cells In Vitro, In a Mouse Xenograft Model and in Human Breast Cancer Tissues

Connexins regulate multiple cellular functions and are considered tumor suppressors. Connexin43 (Cx43) is frequently down-regulated in breast tumors. However, Cx43 regulation during cancer onset and metastasis is complex and context-dependent. We investigated the effect of Cx43 over-expression or kn...

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Detalles Bibliográficos
Autores principales: Kazan, Jalal M., El-Saghir, Jamal, Saliba, Jessica, Shaito, Abdullah, Jalaleddine, Nour, El-Hajjar, Layal, Al-Ghadban, Sara, Yehia, Lamis, Zibara, Kazem, El-Sabban, Marwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521103/
https://www.ncbi.nlm.nih.gov/pubmed/30939738
http://dx.doi.org/10.3390/cancers11040460

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