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Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain
Picrasma quassioides (D. Don) Benn, a medical plant, is used in clinic to treat inflammation, pain, sore throat, and eczema. The alkaloids are the main active components in P. quassioides. In this study, we examined the analgesic effect of dehydrocrenatidine (DHCT), a β-carboline alkaloid abundantly...
Autores principales: | Zhao, Fang, Tang, Qinglian, Xu, Jian, Wang, Shuangyan, Li, Shaoheng, Zou, Xiaohan, Cao, Zhengyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521113/ https://www.ncbi.nlm.nih.gov/pubmed/31003411 http://dx.doi.org/10.3390/toxins11040229 |
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