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Identification of the Actinomycin D Biosynthetic Pathway from Marine-Derived Streptomyces costaricanus SCSIO ZS0073

Bioactive secondary metabolites from Streptomycetes are important sources of lead compounds in current drug development. Streptomyces costaricanus SCSIO ZS0073, a mangrove-derived actinomycete, produces actinomycin D, a clinically used therapeutic for Wilm’s tumor of the kidney, trophoblastic tumors...

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Detalles Bibliográficos
Autores principales:	Liu, Mengchan, Jia, Yanxi, Xie, Yunchang, Zhang, Chunyan, Ma, Junying, Sun, Changli, Ju, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521150/ https://www.ncbi.nlm.nih.gov/pubmed/31018504 http://dx.doi.org/10.3390/md17040240

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