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Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer
The implementation of cancer immunotherapeutics for solid tumors including lung cancers has improved clinical outcomes in a small percentage of patients. However, the majority of patients show little to no response or acquire resistance during treatment with checkpoint inhibitors delivered as a mono...
Autores principales: | Konen, Jessica M., Rodriguez, B. Leticia, Fradette, Jared J., Gibson, Laura, Davis, Denali, Minelli, Rosalba, Peoples, Michael D., Kovacs, Jeffrey, Carugo, Alessandro, Bristow, Christopher, Heffernan, Timothy, Gibbons, Don L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521201/ https://www.ncbi.nlm.nih.gov/pubmed/30986992 http://dx.doi.org/10.3390/cancers11040462 |
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