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All-Trans-Retinoic Acid Suppresses Neointimal Hyperplasia and Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via Activation of AMPK Signaling Pathway

The proliferation and migration of vascular smooth muscle cells (VSMC) is extensively involved in pathogenesis of neointimal hyperplasia. All-trans-retinoic acid (ATRA) is a natural metabolite of vitamin A. Here, we investigated the involvement of AMP-activated protein kinase (AMPK) in the anti-neoi...

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Detalles Bibliográficos
Autores principales: Zhang, Jingzhi, Deng, Bo, Jiang, Xiaoli, Cai, Min, Liu, Ningning, Zhang, Shuangwei, Tan, Yongzhen, Huang, Guiqiong, Jin, Wen, Liu, Bin, Liu, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521230/
https://www.ncbi.nlm.nih.gov/pubmed/31143119
http://dx.doi.org/10.3389/fphar.2019.00485