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All-Trans-Retinoic Acid Suppresses Neointimal Hyperplasia and Inhibits Vascular Smooth Muscle Cell Proliferation and Migration via Activation of AMPK Signaling Pathway
The proliferation and migration of vascular smooth muscle cells (VSMC) is extensively involved in pathogenesis of neointimal hyperplasia. All-trans-retinoic acid (ATRA) is a natural metabolite of vitamin A. Here, we investigated the involvement of AMP-activated protein kinase (AMPK) in the anti-neoi...
Autores principales: | Zhang, Jingzhi, Deng, Bo, Jiang, Xiaoli, Cai, Min, Liu, Ningning, Zhang, Shuangwei, Tan, Yongzhen, Huang, Guiqiong, Jin, Wen, Liu, Bin, Liu, Shiming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521230/ https://www.ncbi.nlm.nih.gov/pubmed/31143119 http://dx.doi.org/10.3389/fphar.2019.00485 |
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