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HOME: a histogram based machine learning approach for effective identification of differentially methylated regions

BACKGROUND: The development of whole genome bisulfite sequencing has made it possible to identify methylation differences at single base resolution throughout an entire genome. However, a persistent challenge in DNA methylome analysis is the accurate identification of differentially methylated regio...

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Detalles Bibliográficos
Autores principales: Srivastava, Akanksha, Karpievitch, Yuliya V., Eichten, Steven R., Borevitz, Justin O., Lister, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521357/
https://www.ncbi.nlm.nih.gov/pubmed/31096906
http://dx.doi.org/10.1186/s12859-019-2845-y