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HOME: a histogram based machine learning approach for effective identification of differentially methylated regions
BACKGROUND: The development of whole genome bisulfite sequencing has made it possible to identify methylation differences at single base resolution throughout an entire genome. However, a persistent challenge in DNA methylome analysis is the accurate identification of differentially methylated regio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521357/ https://www.ncbi.nlm.nih.gov/pubmed/31096906 http://dx.doi.org/10.1186/s12859-019-2845-y |