Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response

BACKGROUND: Blood-brain barrier (BBB) disruption and neuroinflammation are considered key mechanisms of pathogenic Escherichia coli invasion of the brain. However, the specific molecules involved in meningitic E. coli-induced BBB breakdown and neuroinflammatory response remain unclear. Our previous...

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Detalles Bibliográficos
Autores principales: Yang, Rui-Cheng, Qu, Xin-Yi, Xiao, Si-Yu, Li, Liang, Xu, Bo-Jie, Fu, Ji-Yang, Lv, Yu-Jin, Amjad, Nouman, Tan, Chen, Kim, Kwang Sik, Chen, Huan-Chun, Wang, Xiang-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521501/
https://www.ncbi.nlm.nih.gov/pubmed/31092253
http://dx.doi.org/10.1186/s12974-019-1497-1

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