Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report

BACKGROUND: According to WHO, succinate dehydrogenase (SDH)–deficient renal cell carcinoma is characterized by negative immunostaining for SDHB, which remains positive in non-tumor tissue despite germline mutations in the SDHB gene. We now report a patient with a SDHB mutation, c.166_170del (p.Pro56...

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Detalles Bibliográficos
Autores principales: Ugarte-Camara, Marina, Fernandez-Prado, Raul, Lorda, Isabel, Rossello, Gabriela, Gonzalez-Enguita, Carmen, Cannata-Ortiz, Pablo, Ortiz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521540/
https://www.ncbi.nlm.nih.gov/pubmed/31092265
http://dx.doi.org/10.1186/s13000-019-0812-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521540/
https://www.ncbi.nlm.nih.gov/pubmed/31092265
http://dx.doi.org/10.1186/s13000-019-0812-6

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